QUANTITATIVE CHALLENGES IN THE POST-GENOMIC SEQUENCE ERA: A WORKSHOP AND SYMPOSIUM Tuesday, January 11 - Saturday, January 15, 2000

This conference will address the pending completion of the human genome sequencing project, and the resultant change in the focus of quantitative studies of genomic information from the gathering and archiving of genomic data to its analysis and use in prediction and discovery.  Key to this new era is research across many disciplinary interfaces, the development and utilization of new quantitative tools, and the training of individuals who are comfortable and equipped to work at these evolving interfaces.  The symposium is intended to provide an international forum for provocative discussions debating the current state-of-the-art and envisioning future directions for the application of quantitative science to sequence-to-function paradigms in biology.  The primary workshop focus will be the training and exposure of developing interdisciplinary scientists to the many new challenges beyond genome sequencing, and to varied approaches to pursuing scientific careers at the interfaces between the physical/chemical/computational and biological sciences.

PROGRAM:

The La Jolla Interfaces in Science, LJIS, will be hosting a two day workshop on Tuesday, January 11 and Wednesday, January 12 followed by a three day international symposium on Thursday, January 13 - Saturday, January 15.
 

DEADLINES:

Wednesday, September 1 - abstracts for contributed talks

Monday, November 1 - abstracts for posters

Monday, November 15 - last day for early registration $50 discount
 

REGISTRATION:

The registration fees will cover the expenses associated with the daily continental breakfasts, conference breaks, registration and poster session receptions, workshop dinner on Tuesday evening, symposium dinner on Saturday evening, and the Friday afternoon social activity.

The fee for registrations postmarked no later than Monday, November 15 will be $600 for the workshop and symposium and $400 for the symposium only.  The fee for registrations postmarked after Monday, November 15 will be $650 for the workshop and symposium and $450 for the symposium only. Link to registration form to print and send.           Link to an electronic registration form.
 

TRAVEL STIPENDS:

LJIS has travel funds available to cover the registration fee, airfare, and double accommodations for all of The Burroughs Wellcome Fund "Interfaces" Fellows.  If you are a BWF fellow and you have not received your invitation, please have your program administrator contact Cheri Brooks, cbrooks@ucsd.edu.

LJIS has ten travel stipends available for other young researchers to attend the workshop and symposium if they are presenting either a contributed talk or poster.  These stipends will cover the awardees' registration fees and shared accommodations.  If you would like to be considered for one of these stipends, please indicate your interest on the cover sheet that accompanies your abstract.
 

LOCATION:

The workshop and symposium will be held in at the Wyndham Emerald Plaza Hotel in the heart of downtown San Diego's historic Gas Lamp Quarter.  Conveniently situated within walking distance of world class shopping, dining, and entertainment, the Wyndham Emerald Plaza offers convenience as well as luxury with its 100-foot-high glass atrium lobby, beautiful indoor reflecting pools, glass elevators and contemporary sculpture.
 

ACCOMMODATIONS:

A special conference rate of $169 single or double has been negotiated at the Wyndham Emerald Plaza Hotel.  To take advantage of this special conference rate, you must identify yourself as a LJIS'2000 participant.  If you are not receiving a travel stipend for the conference, then you should contact the Wyndham directly to make your reservation.  Their phone number is 1-619-239-4500.  If you are interested in sharing a room with another participant, then please send email to ljis2000@ucsd.edu.
 
 

CONTRIBUTED TALKS:

In addition to invited speakers, there will be ten-twelve fifteen minute contributed talks during the symposium, January 13 - 15, 2000.  These brief talks will spotlight the projects of workshop participants and other young researchers.  Contributed talks included in the program will be selected by the local organizing committee based on abstracts received prior to the Wednesday, September 1 deadline.  Abstracts should be sent to:  LJIS2000, 9500 Gilman Drive MC 0319, La Jolla, CA  92093-0319.  Abstracts may be faxed to LJIS2000 at 858-534-7697 to comply with the deadline, however, hardcopy or electronic files must also be sent.  The abstracts for the contributed talks will be published in the conference program. All abstracts will be reproduced exactly as they are submitted.
 

CONTRIBUTED POSTERS:

There will be poster sessions following the roundtable discussions on the evenings of Thursday, January 13 and Friday, January 14.  Researchers will be invited to present a poster by the local organizing committee based on abstracts received prior to the Monday, November 1 deadline.  All fellows and junior researchers are strongly encouraged to utilize this opportunity to showcase their work.  Abstracts should be sent to:  LJIS2000, 9500 Gilman Drive MC 0319, La Jolla, CA  92093-0319.  Abstracts may be faxed to LJIS2000 at 858-534-7697 to comply with the deadline, however, a hardcopy must also be sent for it to be considered.  The abstracts for the contributed talks will be published in the conference program.  All abstracts will be reproduced exactly as they are submitted.
 

ABSTRACT GUIDELINES:

Abstracts for the featured contributed talks and posters will be published in the conference program book. All abstracts will be reproduced exactly as they are submitted.   Each abstract should be accompanied by a cover sheet that includes the presenter's name, U.S. postal address, electronic address, URL address, phone number, and fax number.  Abstracts must:

• include at the top in bold: Title of Talk/Poster, Authors' Name(s) and Affiliation(s).
• be single spaced, no longer than 5 inches, no wider than 6.5 inches.
• must be in 12 point Times New Roman font.

1) Electronically:  Email the abstract as a Microsoft Word attachment to:  ljis2000@ucsd.edu.  In the body of your message be sure to include the presenter's name, U.S. postal address, electronic address, URL address, phone number, and fax number.

2)  Hard Copy:  Send a hard copy of the abstract with a cover sheet with the presenter's name, U.S. postal address, electronic address, URL address, phone number, and fax number to:  LJIS2000, 9500 Gilman Drive MC 0319, La Jolla, CA  92093-0319.  Abstracts and cover sheets may be faxed to LJIS2000 at 858-534-7697 to comply with the deadline, however, hardcopies must also be sent for the abstract to be considered.
 

WORKSHOP:

The two-day workshop (Tuesday and Wednesday January 11-12, 2000) will feature a series of nine tutorials and lectures by younger researchers.  Each thirty minute lecture will be preceded by a ten minute introduction and followed by a twenty minute open discussion.  Follow this link to the preliminary agenda.

Tuesday, January 11

Exploring the Genome(s) Sequence to Function

• Sequence Organization and Evolution

 
• Functional Exploration via X-Ray Technology

 
• NMR Structure, Function, and Folding

• Modeling Structures of Entire Genomes

 

Understanding the Fundamentals of Structure, Function, and Folding

• Theoretical Basis for Fold Prediction and Folding Mechanism Rationalization

• The Role of Single Molecule Experiments

• Exploring Fast Events in Biological Systems

• Coupling Simulation Theory and Experiment

• Making the Most of Structural Data

 

Each of the symposium's three days (Thursday through Saturday January 13-15, 1999) will have a theme.  These themes are listed below together with presentation areas.  In addition to invited speakers, there will be ten-twelve contributed talks, intended to spotlight the work of workshop participants and other young researchers.  There will also be poster sessions following the roundtable discussions on Thursday and Friday evenings.  Follow this link to the preliminary agenda.
 

Thursday, January 13

Folding the Genome(s) - Sequence to Structure and Beyond

 
• Organization and Rationalization of Genomic Sequence Data: Guidance from Structure Prediction

 
• Hopes and Promise from High Throughput X-Ray Crystallography

 
• Automated Analysis of Protein Structures from NMR Data: Prognosis for Structural Genomics

 
• Roundtable Discussion:

How far can we get with present day technologies?

What further technological advances will help?
 

• Poster Session

Understanding the Genome Structure(s) and Their Connection to Function

 
• The Role of Functional Information in Pre and Post Structure Determination and Analysis:
 Function From Structure, Structure From Function?
• Exploring the Physical Mechanisms that Determine Structure and Function
 
• Understanding Success and Failure in the Prediction and Rationalization of Fold Prediction and Folding Mechanism: Theoretical Framework(s)

• Roundtable Discussion:

What do we understand theoretically and experimentally about the physical mechanisms that determine structure?

Is the current level of knowledge of these mechanisms together with existent structural information sufficient to predict all novel structures using the genomic data?

How much about function can be understood directly from structures and sequences?
 

• Poster Session

 

Exploring Tomorrow's Landscape - From Atomic Details to Molecular Networks

• Advancing Theories Connecting Molecules to Measurements

 
• One Step at a Time, From Seeing Single Molecules to Feeling Them

• Toward the Functionally Connected Genome

• Energetics and Timescales of Fundamental Biological Processes

LJIS:  Cherolyn (Cheri) Brooks is the administrative coordinator for LJIS2000.  She can be reached at cbrooks@ucsd.edu, 858-822-1296, fax 858-534-7697, or 9500 Gilman Drive  MC 0319, La Jolla, CA 92093-0319.

PCMI:  Professional Conference Management, Inc. staff will be processing all the abstract and registration materials in addition to making all the conference arrangements.  They can be reached at pcminc@pcmisandiego.com, 858-565-9921, fax 858-565-9954, or 7916 Convoy Court, San Diego, CA  92111.  When contacting them, please reference LJIS2000.